{"jobs":[{"id":"f7f22110-36e7-4c12-b111-aec537c6826f","title":"Senior Technical Product Manager","department":"AI Research and Engineering","team":"AI Research and Engineering","employmentType":"FullTime","location":"United States - Remote","secondaryLocations":[{"location":"Vancouver, WA","address":{"postalAddress":{"postalCode":"98683","addressRegion":"WA","streetAddress":"18105 SE Mill Plain Blvd","addressCountry":"USA","addressLocality":"Vancouver"}}},{"location":"Absci AI Research Lab","address":{"postalAddress":{"postalCode":"10019","addressRegion":"New York ","streetAddress":"152 West 57th St, 21st Floor","addressCountry":"U.S.A","addressLocality":"New York"}}}],"publishedAt":"2026-08-06T19:33:33.900+00:00","isListed":true,"isRemote":true,"workplaceType":"Remote","address":{"postalAddress":{"addressCountry":"United States"}},"jobUrl":"https://jobs.ashbyhq.com/absci/f7f22110-36e7-4c12-b111-aec537c6826f","applyUrl":"https://jobs.ashbyhq.com/absci/f7f22110-36e7-4c12-b111-aec537c6826f/application","descriptionHtml":"<p style=\"min-height:1.5em\"><strong>About Absci</strong></p><p style=\"min-height:1.5em\">Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets.</p><p style=\"min-height:1.5em\">Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at <a target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"http://www.absci.com\">www.absci.com</a> or follow us on LinkedIn (<a target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"https://www.globenewswire.com/Tracker?data=QKz5HZjFLFcFlte0YrrQC2_RZ9jEfBFXR4U86Ihyw5yW5l0TJ95wXGFPNkalvX5xK_1tEI7VNfv2YrNozFsC63NWGGcJFFgkAi2YmFiJdyU=\"><u>@absci</u></a>), X (<a target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"https://www.globenewswire.com/Tracker?data=4f2_M87IaqlZJFPpkOQk1a253uTPOorDDdYHnQXguGq6ueEuvsZsV2iqFOgeQlUQ6K7ilz9v9z06zj1J7J095A==\"><u>@Abscibio</u></a>), and <a target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"https://www.globenewswire.com/Tracker?data=pFUhTvaKrb8dfcipGtnwTLQqi0USS1LieKqGM4t6Vddl7ktIUkXqFv1wY4ZGCfxiynAyNI9n4LdC1YM1TwQcyE1K6LqS719bn4NSniK2Ab0=\"><u>YouTube</u></a>.</p><p style=\"min-height:1.5em\"></p><p style=\"min-height:1.5em\"><strong>Senior Technical Product Manager (AI Research &amp; Development)</strong></p><p style=\"min-height:1.5em\"><em>Remote within the United States. Hybrid work available in Vancouver, WA; New York City, NY.</em></p><p style=\"min-height:1.5em\"></p><p style=\"min-height:1.5em\">We are currently seeking a <strong>Senior Technical Product Manager</strong> to join our AI Research and Development team. You will be responsible for developing and executing on the vision, strategy, and deployment of both AI and Lab Products at Absci. You will drive small, interdisciplinary teams of Artificial Intelligence (AI) and Machine Learning (ML) Researchers, Software Engineers, Structural Biologists, and Screening  Scientists to build delivery platforms that allow us to design, optimize, and validate biologics for treating conditions like cancer, autoimmune diseases, and infectious diseases. You will serve as a bridge between our AI Research and Biologics Discovery Technology teams, leading initiatives surrounding the development and/or application in one of two key areas:</p><p style=\"min-height:1.5em\"></p><p style=\"min-height:1.5em\"><u>AI-Guided Target Identification</u>: An AI platform that leverages genetic-based evidence to discover novel target-indication pairs and de-risk <em>in vivo</em> or <em>ex vivo</em> pathway validation.</p><p style=\"min-height:1.5em\"></p><p style=\"min-height:1.5em\"><u>AI-Guided Drug Design</u>: A platform that uses generative AI to design and optimize antibody-based drugs to grow Absci’s internal pipeline and deliver on external partnerships.<br /></p><p style=\"min-height:1.5em\"></p><p style=\"min-height:1.5em\"><strong>Responsibilities:</strong></p><ul style=\"min-height:1.5em\"><li><p style=\"min-height:1.5em\">Gather and synthesize product requirements from AI, Engineering, and Wet Lab Scientists and Business Development teams, then drive alignment with leadership for actionable product strategy</p></li><li><p style=\"min-height:1.5em\">Own product roadmaps with decisive precision and bias for action; make trade-off decisions between competing priorities and risk</p></li><li><p style=\"min-height:1.5em\">Partner with managers and technical leads with diverse backgrounds and areas of expertise to establish a cohesive product vision</p></li><li><p style=\"min-height:1.5em\">Build detailed roadmaps, backlogs, and execution plans for assigned domain; partner with management to define OKRs and KPIs; track performance and adjust strategy based on data</p></li><li><p style=\"min-height:1.5em\">Lead cross-functional teams through product initiatives from conception through deployment and optimization, proactively identifying and removing any blockers</p></li><li><p style=\"min-height:1.5em\">Conduct research with product team and potential users to understand needs, pain points, and opportunities</p></li><li><p style=\"min-height:1.5em\">Drive adoption and successful deployment of products within internal programs and external partnerships</p></li></ul><p style=\"min-height:1.5em\"></p><p style=\"min-height:1.5em\"><strong>Qualifications:</strong></p><ul style=\"min-height:1.5em\"><li><p style=\"min-height:1.5em\">Bachelor's degree in Computer Science, Bioinformatics, Data Science, Engineering, Life Sciences, or related field</p></li><li><p style=\"min-height:1.5em\">At least 5 years of professional experience working on production-grade software or technical products development</p></li><li><p style=\"min-height:1.5em\">3+ years of working or educational experience in AI/ML and/or Protein Engineering</p></li><li><p style=\"min-height:1.5em\">Strong technical knowledge to enable effective collaboration with world-class engineers and scientists</p></li><li><p style=\"min-height:1.5em\">Proven track record of creating and executing on product roadmaps to deliver high-impact work</p></li><li><p style=\"min-height:1.5em\">Demonstrated ability to manage complex stakeholder relationships across diverse teams</p></li><li><p style=\"min-height:1.5em\">Excellent written and oral communication skills; ability to explain complex technical and business concepts</p></li><li><p style=\"min-height:1.5em\">Excellent organizational skills and ability to manage multiple competing priorities</p></li><li><p style=\"min-height:1.5em\">Comfortable working in a fast-paced environment with autonomy, accountability, and bias for action</p></li></ul><p style=\"min-height:1.5em\"></p><p style=\"min-height:1.5em\"><strong>Preferred (but not required):</strong></p><ul style=\"min-height:1.5em\"><li><p style=\"min-height:1.5em\">Masters or PhD degree in relevant field</p></li><li><p style=\"min-height:1.5em\">Experience in the Biotech or Pharmaceutical Industries</p></li><li><p style=\"min-height:1.5em\">Experience with generative AI (GenAI), NLP, or computer vision, large language models (LLMs), or protein language models</p></li><li><p style=\"min-height:1.5em\">Experience with MLOps tools such as Weights &amp; Biases</p></li><li><p style=\"min-height:1.5em\">Deep knowledge of bioinformatics, computational protein design, computational genomics, immunology, structural biology, antibody engineering, or related fields</p></li><li><p style=\"min-height:1.5em\">Experience with NGS, SPR, or Flow Cytometry data</p></li><li><p style=\"min-height:1.5em\">Experience as an agile coach, product owner, or Scrum Master</p></li></ul><p style=\"min-height:1.5em\"></p><p style=\"min-height:1.5em\">The salary range for US-based employees in this position is $145,000 - $180,000/year. Competitive equity package applies. Pay offered may vary depending on job-related knowledge, skills, and experience. In addition to equity, compensation packages include a wide range of medical, dental, vision benefits and ability to participate in our employee stock purchase plan.</p><p style=\"min-height:1.5em\"></p><p style=\"min-height:1.5em\">Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which they have applied should make a request to the recruiter or hiring manager, or contact hiring@absci.com.</p>","descriptionPlain":"About Absci\n\nAbsci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets.\n\nAbsci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com http://www.absci.com or follow us on LinkedIn (@absci https://www.globenewswire.com/Tracker?data=QKz5HZjFLFcFlte0YrrQC2_RZ9jEfBFXR4U86Ihyw5yW5l0TJ95wXGFPNkalvX5xK_1tEI7VNfv2YrNozFsC63NWGGcJFFgkAi2YmFiJdyU=), X (@Abscibio https://www.globenewswire.com/Tracker?data=4f2_M87IaqlZJFPpkOQk1a253uTPOorDDdYHnQXguGq6ueEuvsZsV2iqFOgeQlUQ6K7ilz9v9z06zj1J7J095A==), and YouTube https://www.globenewswire.com/Tracker?data=pFUhTvaKrb8dfcipGtnwTLQqi0USS1LieKqGM4t6Vddl7ktIUkXqFv1wY4ZGCfxiynAyNI9n4LdC1YM1TwQcyE1K6LqS719bn4NSniK2Ab0=.\n\n\n\nSenior Technical Product Manager (AI Research & Development)\n\nRemote within the United States. Hybrid work available in Vancouver, WA; New York City, NY.\n\n\n\nWe are currently seeking a Senior Technical Product Manager to join our AI Research and Development team. You will be responsible for developing and executing on the vision, strategy, and deployment of both AI and Lab Products at Absci. You will drive small, interdisciplinary teams of Artificial Intelligence (AI) and Machine Learning (ML) Researchers, Software Engineers, Structural Biologists, and Screening  Scientists to build delivery platforms that allow us to design, optimize, and validate biologics for treating conditions like cancer, autoimmune diseases, and infectious diseases. You will serve as a bridge between our AI Research and Biologics Discovery Technology teams, leading initiatives surrounding the development and/or application in one of two key areas:\n\n\n\nAI-Guided Target Identification: An AI platform that leverages genetic-based evidence to discover novel target-indication pairs and de-risk in vivo or ex vivo pathway validation.\n\n\n\nAI-Guided Drug Design: A platform that uses generative AI to design and optimize antibody-based drugs to grow Absci’s internal pipeline and deliver on external partnerships.\n\n\n\n\nResponsibilities:\n\n - Gather and synthesize product requirements from AI, Engineering, and Wet Lab Scientists and Business Development teams, then drive alignment with leadership for actionable product strategy\n\n - Own product roadmaps with decisive precision and bias for action; make trade-off decisions between competing priorities and risk\n\n - Partner with managers and technical leads with diverse backgrounds and areas of expertise to establish a cohesive product vision\n\n - Build detailed roadmaps, backlogs, and execution plans for assigned domain; partner with management to define OKRs and KPIs; track performance and adjust strategy based on data\n\n - Lead cross-functional teams through product initiatives from conception through deployment and optimization, proactively identifying and removing any blockers\n\n - Conduct research with product team and potential users to understand needs, pain points, and opportunities\n\n - Drive adoption and successful deployment of products within internal programs and external partnerships\n\n\n\nQualifications:\n\n - Bachelor's degree in Computer Science, Bioinformatics, Data Science, Engineering, Life Sciences, or related field\n\n - At least 5 years of professional experience working on production-grade software or technical products development\n\n - 3+ years of working or educational experience in AI/ML and/or Protein Engineering\n\n - Strong technical knowledge to enable effective collaboration with world-class engineers and scientists\n\n - Proven track record of creating and executing on product roadmaps to deliver high-impact work\n\n - Demonstrated ability to manage complex stakeholder relationships across diverse teams\n\n - Excellent written and oral communication skills; ability to explain complex technical and business concepts\n\n - Excellent organizational skills and ability to manage multiple competing priorities\n\n - Comfortable working in a fast-paced environment with autonomy, accountability, and bias for action\n\n\n\nPreferred (but not required):\n\n - Masters or PhD degree in relevant field\n\n - Experience in the Biotech or Pharmaceutical Industries\n\n - Experience with generative AI (GenAI), NLP, or computer vision, large language models (LLMs), or protein language models\n\n - Experience with MLOps tools such as Weights & Biases\n\n - Deep knowledge of bioinformatics, computational protein design, computational genomics, immunology, structural biology, antibody engineering, or related fields\n\n - Experience with NGS, SPR, or Flow Cytometry data\n\n - Experience as an agile coach, product owner, or Scrum Master\n\n\n\nThe salary range for US-based employees in this position is $145,000 - $180,000/year. Competitive equity package applies. Pay offered may vary depending on job-related knowledge, skills, and experience. In addition to equity, compensation packages include a wide range of medical, dental, vision benefits and ability to participate in our employee stock purchase plan.\n\n\n\nLegal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which they have applied should make a request to the recruiter or hiring manager, or contact hiring@absci.com."},{"id":"753cbb4f-f019-459b-b06e-659e30094d86","title":"Senior/Staff AI Scientist, Antibody Design ","department":"AI Research and Engineering","team":"AI Research and Engineering","employmentType":"FullTime","location":"United States - Remote","secondaryLocations":[],"publishedAt":"2026-08-21T20:33:43.049+00:00","isListed":true,"isRemote":true,"workplaceType":"Remote","address":{"postalAddress":{"addressCountry":"United States"}},"jobUrl":"https://jobs.ashbyhq.com/absci/753cbb4f-f019-459b-b06e-659e30094d86","applyUrl":"https://jobs.ashbyhq.com/absci/753cbb4f-f019-459b-b06e-659e30094d86/application","descriptionHtml":"<p style=\"min-height:1.5em\"><strong>About Absci</strong></p><p style=\"min-height:1.5em\">Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets.</p><p style=\"min-height:1.5em\">Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at <a target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"http://www.absci.com\">www.absci.com</a> or follow us on LinkedIn (<a target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"https://www.globenewswire.com/Tracker?data=QKz5HZjFLFcFlte0YrrQC2_RZ9jEfBFXR4U86Ihyw5yW5l0TJ95wXGFPNkalvX5xK_1tEI7VNfv2YrNozFsC63NWGGcJFFgkAi2YmFiJdyU=\"><u>@absci</u></a>), X (<a target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"https://www.globenewswire.com/Tracker?data=4f2_M87IaqlZJFPpkOQk1a253uTPOorDDdYHnQXguGq6ueEuvsZsV2iqFOgeQlUQ6K7ilz9v9z06zj1J7J095A==\"><u>@Abscibio</u></a>), and <a target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"https://www.globenewswire.com/Tracker?data=pFUhTvaKrb8dfcipGtnwTLQqi0USS1LieKqGM4t6Vddl7ktIUkXqFv1wY4ZGCfxiynAyNI9n4LdC1YM1TwQcyE1K6LqS719bn4NSniK2Ab0=\"><u>YouTube</u></a>.</p><p style=\"min-height:1.5em\"></p><p style=\"min-height:1.5em\"><strong>About the role</strong></p><p style=\"min-height:1.5em\">Absci is looking for a Senior/Staff AI Scientist to advance and deploy protein design models for antibody drug design. In this role, you will apply your broad expertise across specialized disciplines in AI Drug Discovery. We are looking for exceptional contributors with backgrounds in deep learning, protein design and engineering, drug discovery, natural language processing, computer vision, and molecular dynamics to develop innovative approaches to creating and assessing therapeutic antibodies <em>in silico.</em></p><p style=\"min-height:1.5em\">Absci offers AI Scientists a unique opportunity to both develop novel, cutting edge machine learning models and apply these models directly to identify novel targets, unlocking previously intractable disease interventions, and to generate candidate antibody therapeutics.</p><p style=\"min-height:1.5em\"><em>This is a remote position, with the option to work onsite at our New York City office or our Vancouver, WA headquarters if located within commuting distance</em></p><p style=\"min-height:1.5em\"><strong>Why Absci’s AI team?</strong></p><p style=\"min-height:1.5em\">Absci offers AI Scientists a unique opportunity to both develop novel, cutting edge machine learning models and apply these models directly to identify novel targets, unlocking previously intractable disease interventions, and to generate candidate antibody therapeutics. In particular we:</p><ul style=\"min-height:1.5em\"><li><p style=\"min-height:1.5em\">Provide our AI Scientists with access to industry-leading compute resources, enabling large-scale experimentation for model training and deployment</p></li><li><p style=\"min-height:1.5em\">Maintain our own Wet Lab, enabling AI Scientists to validate novel modeling methods via rapid design &gt; build &gt; test &gt; learn cycles</p></li><li><p style=\"min-height:1.5em\">Developed and are growing our own pipeline of clinical-stage assets, enabling AI Scientists to see their work directly translated into therapeutic impact for patients</p></li></ul><p style=\"min-height:1.5em\"></p><p style=\"min-height:1.5em\"><strong>Responsibilities</strong></p><ul style=\"min-height:1.5em\"><li><p style=\"min-height:1.5em\">Partner with team members across AI Research, AI Engineering, Computational Biology, and Protein Engineering to achieve success along the following axes:</p><ul style=\"min-height:1.5em\"><li><p style=\"min-height:1.5em\">Novel test-time compute strategies that maximize the quality and efficiency of our design pipelines.</p></li><li><p style=\"min-height:1.5em\">Multi-objective optimization of therapeutic design goals</p></li><li><p style=\"min-height:1.5em\">Solve key challenges of per-target design specification via innovative, AI-driven solutions.</p></li></ul></li><li><p style=\"min-height:1.5em\">Analyze <em>in silico</em> and <em>in vitro</em> validation results to iteratively improve design and evaluation methodologies</p></li><li><p style=\"min-height:1.5em\">Develop, deliver and publish high-impact research that advances Absci’s position as a thought leader in the field of AI antibody design</p></li><li><p style=\"min-height:1.5em\">Invest in ensuring work is accessible and interpretable to scientists with other domain expertise.</p></li><li><p style=\"min-height:1.5em\">Ability and willingness to learn new technical skills to improve scientific contributions</p></li></ul><p style=\"min-height:1.5em\"></p><p style=\"min-height:1.5em\"><strong>Qualifications</strong></p><ul style=\"min-height:1.5em\"><li><p style=\"min-height:1.5em\">PhD or equivalent experience in Machine Learning, Computer Science, Computational Biology, Computational Chemistry, Biophysics, or a related field</p></li><li><p style=\"min-height:1.5em\">3+ years of research experience at the intersection of machine learning and protein design, molecular modeling, or a related field, ideally including industry experience.</p></li><li><p style=\"min-height:1.5em\">Fluency in Python and PyTorch</p></li><li><p style=\"min-height:1.5em\">Comfortable with design, implementation, and evaluation of state-of-the-art AI algorithms for protein design and protein structure prediction</p></li><li><p style=\"min-height:1.5em\">Demonstrated ability to work collaboratively in an ambitious, fast-paced, interdisciplinary environment</p></li><li><p style=\"min-height:1.5em\">Demonstrated experience presenting complex technical work to diverse audiences</p></li><li><p style=\"min-height:1.5em\">Strong publication record in respected, high-impact journals and conferences</p></li></ul><p style=\"min-height:1.5em\">Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which they have applied should make a request to the recruiter or hiring manager, or contact hiring@absci.com.</p>","descriptionPlain":"About Absci\n\nAbsci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets.\n\nAbsci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com http://www.absci.com or follow us on LinkedIn (@absci https://www.globenewswire.com/Tracker?data=QKz5HZjFLFcFlte0YrrQC2_RZ9jEfBFXR4U86Ihyw5yW5l0TJ95wXGFPNkalvX5xK_1tEI7VNfv2YrNozFsC63NWGGcJFFgkAi2YmFiJdyU=), X (@Abscibio https://www.globenewswire.com/Tracker?data=4f2_M87IaqlZJFPpkOQk1a253uTPOorDDdYHnQXguGq6ueEuvsZsV2iqFOgeQlUQ6K7ilz9v9z06zj1J7J095A==), and YouTube https://www.globenewswire.com/Tracker?data=pFUhTvaKrb8dfcipGtnwTLQqi0USS1LieKqGM4t6Vddl7ktIUkXqFv1wY4ZGCfxiynAyNI9n4LdC1YM1TwQcyE1K6LqS719bn4NSniK2Ab0=.\n\n\n\nAbout the role\n\nAbsci is looking for a Senior/Staff AI Scientist to advance and deploy protein design models for antibody drug design. In this role, you will apply your broad expertise across specialized disciplines in AI Drug Discovery. We are looking for exceptional contributors with backgrounds in deep learning, protein design and engineering, drug discovery, natural language processing, computer vision, and molecular dynamics to develop innovative approaches to creating and assessing therapeutic antibodies in silico.\n\nAbsci offers AI Scientists a unique opportunity to both develop novel, cutting edge machine learning models and apply these models directly to identify novel targets, unlocking previously intractable disease interventions, and to generate candidate antibody therapeutics.\n\nThis is a remote position, with the option to work onsite at our New York City office or our Vancouver, WA headquarters if located within commuting distance\n\nWhy Absci’s AI team?\n\nAbsci offers AI Scientists a unique opportunity to both develop novel, cutting edge machine learning models and apply these models directly to identify novel targets, unlocking previously intractable disease interventions, and to generate candidate antibody therapeutics. In particular we:\n\n - Provide our AI Scientists with access to industry-leading compute resources, enabling large-scale experimentation for model training and deployment\n\n - Maintain our own Wet Lab, enabling AI Scientists to validate novel modeling methods via rapid design > build > test > learn cycles\n\n - Developed and are growing our own pipeline of clinical-stage assets, enabling AI Scientists to see their work directly translated into therapeutic impact for patients\n\n\n\nResponsibilities\n\n - Partner with team members across AI Research, AI Engineering, Computational Biology, and Protein Engineering to achieve success along the following axes:\n   \n   - Novel test-time compute strategies that maximize the quality and efficiency of our design pipelines.\n   \n   - Multi-objective optimization of therapeutic design goals\n   \n   - Solve key challenges of per-target design specification via innovative, AI-driven solutions.\n\n - Analyze in silico and in vitro validation results to iteratively improve design and evaluation methodologies\n\n - Develop, deliver and publish high-impact research that advances Absci’s position as a thought leader in the field of AI antibody design\n\n - Invest in ensuring work is accessible and interpretable to scientists with other domain expertise.\n\n - Ability and willingness to learn new technical skills to improve scientific contributions\n\n\n\nQualifications\n\n - PhD or equivalent experience in Machine Learning, Computer Science, Computational Biology, Computational Chemistry, Biophysics, or a related field\n\n - 3+ years of research experience at the intersection of machine learning and protein design, molecular modeling, or a related field, ideally including industry experience.\n\n - Fluency in Python and PyTorch\n\n - Comfortable with design, implementation, and evaluation of state-of-the-art AI algorithms for protein design and protein structure prediction\n\n - Demonstrated ability to work collaboratively in an ambitious, fast-paced, interdisciplinary environment\n\n - Demonstrated experience presenting complex technical work to diverse audiences\n\n - Strong publication record in respected, high-impact journals and conferences\n\nLegal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which they have applied should make a request to the recruiter or hiring manager, or contact hiring@absci.com."},{"id":"e976ca86-4a93-449f-8f9c-882679988473","title":"Senior/Staff AI Scientist, Target Discovery","department":"AI Research and Engineering","team":"AI Research and Engineering","employmentType":"FullTime","location":"United States - Remote","secondaryLocations":[],"publishedAt":"2026-08-21T20:32:07.171+00:00","isListed":true,"isRemote":true,"workplaceType":"Remote","address":{"postalAddress":{"addressCountry":"United States"}},"jobUrl":"https://jobs.ashbyhq.com/absci/e976ca86-4a93-449f-8f9c-882679988473","applyUrl":"https://jobs.ashbyhq.com/absci/e976ca86-4a93-449f-8f9c-882679988473/application","descriptionHtml":"<p style=\"min-height:1.5em\"><strong>About Absci</strong></p><p style=\"min-height:1.5em\">Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets.</p><p style=\"min-height:1.5em\">Absci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at <a target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"http://www.absci.com\">www.absci.com</a> or follow us on LinkedIn (<a target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"https://www.globenewswire.com/Tracker?data=QKz5HZjFLFcFlte0YrrQC2_RZ9jEfBFXR4U86Ihyw5yW5l0TJ95wXGFPNkalvX5xK_1tEI7VNfv2YrNozFsC63NWGGcJFFgkAi2YmFiJdyU=\"><u>@absci</u></a>), X (<a target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"https://www.globenewswire.com/Tracker?data=4f2_M87IaqlZJFPpkOQk1a253uTPOorDDdYHnQXguGq6ueEuvsZsV2iqFOgeQlUQ6K7ilz9v9z06zj1J7J095A==\"><u>@Abscibio</u></a>), and <a target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"https://www.globenewswire.com/Tracker?data=pFUhTvaKrb8dfcipGtnwTLQqi0USS1LieKqGM4t6Vddl7ktIUkXqFv1wY4ZGCfxiynAyNI9n4LdC1YM1TwQcyE1K6LqS719bn4NSniK2Ab0=\"><u>YouTube</u></a>.</p><p style=\"min-height:1.5em\"></p><p style=\"min-height:1.5em\"><strong>About the role</strong></p><p style=\"min-height:1.5em\">Absci is looking for a Senior/Staff AI Scientist to advance and deploy protein design models for antibody drug design. In this role, you will apply your broad expertise across specialized disciplines in AI Drug Discovery. We are looking for exceptional contributors with backgrounds in deep learning, protein design and engineering, drug discovery, natural language processing, computer vision, and molecular dynamics to develop innovative approaches to creating and assessing therapeutic antibodies <em>in silico.</em></p><p style=\"min-height:1.5em\">Absci offers AI Scientists a unique opportunity to both develop novel, cutting edge machine learning models and apply these models directly to identify novel targets, unlocking previously intractable disease interventions, and to generate candidate antibody therapeutics.</p><p style=\"min-height:1.5em\"><em>This is a remote position, with the option to work onsite at our New York City office or our Vancouver, WA headquarters if within commuting distance</em></p><p style=\"min-height:1.5em\"></p><p style=\"min-height:1.5em\"><strong>Why Absci’s AI team?</strong></p><p style=\"min-height:1.5em\">Absci offers AI Scientists a unique opportunity to both develop novel, cutting edge machine learning models and apply these models directly to identify novel targets, unlocking previously intractable disease interventions, and to generate candidate antibody therapeutics. In particular we:</p><ul style=\"min-height:1.5em\"><li><p style=\"min-height:1.5em\">Provide our AI Scientists with access to industry-leading compute resources, enabling large-scale experimentation for model training and deployment</p></li><li><p style=\"min-height:1.5em\">Maintain our own Wet Lab, enabling AI Scientists to validate novel modeling methods via rapid design &gt; build &gt; test &gt; learn cycles</p></li><li><p style=\"min-height:1.5em\">Developed and are growing our own pipeline of clinical-stage assets, enabling AI Scientists to see their work directly translated into therapeutic impact for patients</p><p style=\"min-height:1.5em\"></p></li></ul><p style=\"min-height:1.5em\"><strong>Key Responsibilities</strong></p><ul style=\"min-height:1.5em\"><li><p style=\"min-height:1.5em\">Develop, adapt, and deploy deep learning models that predict the intra- and intercellular signaling effects of potential therapeutic interventions</p></li><li><p style=\"min-height:1.5em\">Design experiments which generate data to train and validate systems biology models</p></li><li><p style=\"min-height:1.5em\">Collaborate closely with cross-functional teams comprising Disease Biologists, Structural Biologists, Computational Biologists, and Wet Lab scientists to define and address the problem space within specific indications</p></li><li><p style=\"min-height:1.5em\">Develop <em>in silico</em> and <em>in vitro</em> validation approaches to iteratively improve design and evaluation methodologies</p></li><li><p style=\"min-height:1.5em\">Communicate and present experimental results in a manner that is accessible to audiences with highly-diverse backgrounds, driving discussions that lead to high-quality, informed decision-making and program progression</p></li><li><p style=\"min-height:1.5em\">Deliver and publish high-impact research that advances Absci’s position as a leader in AI-guided antibody therapeutic discovery</p></li><li><p style=\"min-height:1.5em\">Actively develop organizational talent through coaching and mentoring other Scientists and Engineers</p></li><li><p style=\"min-height:1.5em\">Ability and willingness to learn new technical skills to improve scientific contributions</p><p style=\"min-height:1.5em\"></p></li></ul><p style=\"min-height:1.5em\"><strong>Qualifications</strong></p><ul style=\"min-height:1.5em\"><li><p style=\"min-height:1.5em\">PhD or equivalent experience in Machine Learning, Computer Science, Computational Biology, Computational Chemistry, Biophysics, or a related field</p></li><li><p style=\"min-height:1.5em\">Seasoned deep learning expert with 3+ years of post-graduate experience and a strong background in several of the following areas: biological world models, mathematical biology, systems biology, disease biology, computational biology/multi-omics, experiment design to generate and/or handling intra- and intercellular perturbation datasets</p></li><li><p style=\"min-height:1.5em\">Fluency in Python and PyTorch</p></li><li><p style=\"min-height:1.5em\">Expertise in large-scale model architecture design and training</p></li><li><p style=\"min-height:1.5em\">Mastery of proper scoring rules, validation metrics for highly imbalanced biological datasets, and active learning paradigms.</p></li><li><p style=\"min-height:1.5em\">Demonstrated ability to work collaboratively in an ambitious, fast-paced, interdisciplinary environment</p></li><li><p style=\"min-height:1.5em\">Demonstrated experience presenting complex technical work to diverse audiences</p></li><li><p style=\"min-height:1.5em\">Strong publication record in respected, high-impact journals and conferences</p></li></ul><p style=\"min-height:1.5em\">Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which they have applied should make a request to the recruiter or hiring manager, or contact hiring@absci.com.</p>","descriptionPlain":"About Absci\n\nAbsci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation™ platform combines cutting-edge AI models with a synthetic biology data engine, enabling the rapid design of innovative therapeutics that address challenging therapeutic targets.\n\nAbsci is a global company headquartered in Vancouver, WA, and maintains offices in New York City, Switzerland, and Serbia. Learn more at www.absci.com http://www.absci.com or follow us on LinkedIn (@absci https://www.globenewswire.com/Tracker?data=QKz5HZjFLFcFlte0YrrQC2_RZ9jEfBFXR4U86Ihyw5yW5l0TJ95wXGFPNkalvX5xK_1tEI7VNfv2YrNozFsC63NWGGcJFFgkAi2YmFiJdyU=), X (@Abscibio https://www.globenewswire.com/Tracker?data=4f2_M87IaqlZJFPpkOQk1a253uTPOorDDdYHnQXguGq6ueEuvsZsV2iqFOgeQlUQ6K7ilz9v9z06zj1J7J095A==), and YouTube https://www.globenewswire.com/Tracker?data=pFUhTvaKrb8dfcipGtnwTLQqi0USS1LieKqGM4t6Vddl7ktIUkXqFv1wY4ZGCfxiynAyNI9n4LdC1YM1TwQcyE1K6LqS719bn4NSniK2Ab0=.\n\n\n\nAbout the role\n\nAbsci is looking for a Senior/Staff AI Scientist to advance and deploy protein design models for antibody drug design. In this role, you will apply your broad expertise across specialized disciplines in AI Drug Discovery. We are looking for exceptional contributors with backgrounds in deep learning, protein design and engineering, drug discovery, natural language processing, computer vision, and molecular dynamics to develop innovative approaches to creating and assessing therapeutic antibodies in silico.\n\nAbsci offers AI Scientists a unique opportunity to both develop novel, cutting edge machine learning models and apply these models directly to identify novel targets, unlocking previously intractable disease interventions, and to generate candidate antibody therapeutics.\n\nThis is a remote position, with the option to work onsite at our New York City office or our Vancouver, WA headquarters if within commuting distance\n\n\n\nWhy Absci’s AI team?\n\nAbsci offers AI Scientists a unique opportunity to both develop novel, cutting edge machine learning models and apply these models directly to identify novel targets, unlocking previously intractable disease interventions, and to generate candidate antibody therapeutics. In particular we:\n\n - Provide our AI Scientists with access to industry-leading compute resources, enabling large-scale experimentation for model training and deployment\n\n - Maintain our own Wet Lab, enabling AI Scientists to validate novel modeling methods via rapid design > build > test > learn cycles\n\n - Developed and are growing our own pipeline of clinical-stage assets, enabling AI Scientists to see their work directly translated into therapeutic impact for patients\n   \n   \n\nKey Responsibilities\n\n - Develop, adapt, and deploy deep learning models that predict the intra- and intercellular signaling effects of potential therapeutic interventions\n\n - Design experiments which generate data to train and validate systems biology models\n\n - Collaborate closely with cross-functional teams comprising Disease Biologists, Structural Biologists, Computational Biologists, and Wet Lab scientists to define and address the problem space within specific indications\n\n - Develop in silico and in vitro validation approaches to iteratively improve design and evaluation methodologies\n\n - Communicate and present experimental results in a manner that is accessible to audiences with highly-diverse backgrounds, driving discussions that lead to high-quality, informed decision-making and program progression\n\n - Deliver and publish high-impact research that advances Absci’s position as a leader in AI-guided antibody therapeutic discovery\n\n - Actively develop organizational talent through coaching and mentoring other Scientists and Engineers\n\n - Ability and willingness to learn new technical skills to improve scientific contributions\n   \n   \n\nQualifications\n\n - PhD or equivalent experience in Machine Learning, Computer Science, Computational Biology, Computational Chemistry, Biophysics, or a related field\n\n - Seasoned deep learning expert with 3+ years of post-graduate experience and a strong background in several of the following areas: biological world models, mathematical biology, systems biology, disease biology, computational biology/multi-omics, experiment design to generate and/or handling intra- and intercellular perturbation datasets\n\n - Fluency in Python and PyTorch\n\n - Expertise in large-scale model architecture design and training\n\n - Mastery of proper scoring rules, validation metrics for highly imbalanced biological datasets, and active learning paradigms.\n\n - Demonstrated ability to work collaboratively in an ambitious, fast-paced, interdisciplinary environment\n\n - Demonstrated experience presenting complex technical work to diverse audiences\n\n - Strong publication record in respected, high-impact journals and conferences\n\nLegal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, sexual orientation, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, marital status, or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which they have applied should make a request to the recruiter or hiring manager, or contact hiring@absci.com."}],"apiVersion":"1"}