Nearly every disease will become treatable in our lifetimes. Mandolin is laying the clinical and financial infrastructure to get groundbreaking treatments to patients faster, powered by AI agents.
Mandolin partners closely with the largest healthcare institutions in the US, covering more than $10B drug spend across the country. We're backed by Greylock, SV Angel, Maverick, SignalFire, and the founders of Vercel, Decagon, and Yahoo.
Mandolin’s agent platform is redefining how healthcare and life sciences organizations operate—bringing AI-driven decision-making and automation to some of the most complex, high-stakes workflows in the industry. Our Product Managers sit at the intersection of deep technical problem solving and customer-centric discovery.
As a Product Manager at Mandolin, you’ll own core modules of our platform while also embedding with customers to understand their most complex workflows. You’ll translate those insights into AI-driven solutions that are reliable, intuitive, and scalable. This is a highly cross-functional, customer-facing role that will shape both Mandolin’s product and the way healthcare organizations operate.
Own the strategy, roadmap, and execution for one or more core product modules.
Partner directly with customers, clinicians, and enterprise stakeholders to uncover workflows and pain points.
Translate field insights into actionable requirements and a clear roadmap for Engineering and Design.
Drive the full product lifecycle—discovery, design, launch, and iteration—balancing speed with long-term scalability.
Define and track success metrics using data and customer feedback to guide prioritization.
Collaborate closely with Engineering, Customer Success, and Deployment Strategists to ensure end-to-end delivery and adoption.
Advocate for customer needs while aligning with Mandolin’s broader company strategy.
5+ years of product management (or equivalent) in enterprise SaaS, AI/automation, or complex workflows.
Proven ability to own a product area end-to-end—from strategy through delivery.
Strong technical fluency; able to engage engineers on APIs, integrations, systems tradeoffs, and AI-powered workflows.
Excellent customer-facing skills—adept at embedding with users, conducting research, and translating insights into solutions.
Strong communicator with relationship-building skills across technical and business stakeholders.
Comfortable operating in fast-paced, ambiguous, and early-stage environments.
Experience building or deploying AI/LLM-powered products in production.
Domain expertise in healthcare, life sciences, biotech, or enterprise operations.
Prior customer-facing experience in deployment strategy, solutions engineering, or consulting.
Familiarity with agent frameworks (e.g., AutoGen, CrewAI, LangGraph) or workflow orchestration tools.
Strong product instincts with a bias toward experimentation and iteration.
Nearly every disease will become treatable in our lifetimes. Mandolin is laying the clinical and financial infrastructure to get groundbreaking treatments to patients faster, powered by AI agents.
Mandolin partners closely with the largest healthcare institutions in the US, covering more than $10B drug spend across the country. We're backed by Greylock, SV Angel, Maverick, SignalFire, and the founders of Vercel, Decagon, and Yahoo.
Mandolin is building the “last-mile” delivery infrastructure that gets cutting-edge biologics, cell, and gene therapies to patients faster. As one of our product engineers, you’ll be directly responsible for shaping the user-facing experiences that our customers rely on daily. This is a hands-on, full-stack role where you’ll bring new product features to life end-to-end—from backend architecture to polished front-end experiences—while establishing the technical patterns that will scale with our growth.
Design, build, and ship full-stack product features across Mandolin’s core modules.
Collaborate closely with Product to scope requirements and translate them into technical implementations.
Own projects end-to-end: backend services, APIs, data flows, and front-end interfaces.
Establish engineering patterns and best practices that ensure quality, maintainability, and scalability as the product evolves.
Participate in code reviews, architecture discussions, and technical decision-making across the team.
Debug, test, and continuously improve our systems to deliver reliable experiences in healthcare-critical environments.
Stay close to customer needs by working alongside our PMs and implementation teams.
4+ years of professional software engineering experience, with strong contributions to full-stack applications.
Proficiency with modern web frameworks (e.g., React, Next.js, or similar) and backend services (e.g., Node.js, Python, Go, or similar).
Experience designing and consuming APIs, working with databases, and building secure, reliable systems.
Track record of owning projects end-to-end in a fast-paced, collaborative environment.
Strong communication skills and a product-minded approach—comfortable working directly with Product and our customers.
Experience working in early-stage startups and shaping product from 0 to 1.
Background in healthcare, life sciences, or other regulated industries.
Familiarity with cloud infrastructure (AWS/GCP), CI/CD pipelines, and monitoring/observability tools.
Exposure to AI-driven products or agentic systems.
Compensation Philosophy
Compensation for this position will include a base salary, equity, and a variety of comprehensive benefits. The U.S. base salary range for this role is $160,000 - $270,000. Actual base salaries will be based on candidate-specific factors, including experience, skillset, and location, and local minimum pay requirements as applicable.
Benefits & Perks
As part of our total rewards package, we offer attractive benefits and perks to our employees, including:
Free lunch in the office daily & dinner if you're in the office past 7PM
Comprehensive health, dental, & vision insurance for you and your family
Life insurance
10 company holidays
Take what you need PTO
4% 401k matching
$300/month company-sponsored commuter benefits
State of the art gym in the office
And more!
Please note the above benefits & perks are for full-time employees
","descriptionPlain":"ABOUT MANDOLIN\n\nNearly every disease will become treatable in our lifetimes. Mandolin is laying the clinical and financial infrastructure to get groundbreaking treatments to patients faster, powered by AI agents.\n\n\n\nMandolin partners closely with the largest healthcare institutions in the US, covering more than $10B drug spend across the country. We're backed by Greylock, SV Angel, Maverick, SignalFire, and the founders of Vercel, Decagon, and Yahoo.\n\n\n\n\nWHY WE NEED YOU\n\nMandolin is building the “last-mile” delivery infrastructure that gets cutting-edge biologics, cell, and gene therapies to patients faster. As one of our product engineers, you’ll be directly responsible for shaping the user-facing experiences that our customers rely on daily. This is a hands-on, full-stack role where you’ll bring new product features to life end-to-end—from backend architecture to polished front-end experiences—while establishing the technical patterns that will scale with our growth.\n\n\n\n\nWHAT YOU’LL DO\n\n - Design, build, and ship full-stack product features across Mandolin’s core modules.\n\n - Collaborate closely with Product to scope requirements and translate them into technical implementations.\n\n - Own projects end-to-end: backend services, APIs, data flows, and front-end interfaces.\n\n - Establish engineering patterns and best practices that ensure quality, maintainability, and scalability as the product evolves.\n\n - Participate in code reviews, architecture discussions, and technical decision-making across the team.\n\n - Debug, test, and continuously improve our systems to deliver reliable experiences in healthcare-critical environments.\n\n - Stay close to customer needs by working alongside our PMs and implementation teams.\n \n \n\n\nMUST-HAVE EXPERIENCE\n\n - 4+ years of professional software engineering experience, with strong contributions to full-stack applications.\n\n - Proficiency with modern web frameworks (e.g., React, Next.js, or similar) and backend services (e.g., Node.js, Python, Go, or similar).\n\n - Experience designing and consuming APIs, working with databases, and building secure, reliable systems.\n\n - Track record of owning projects end-to-end in a fast-paced, collaborative environment.\n\n - Strong communication skills and a product-minded approach—comfortable working directly with Product and our customers.\n \n \n\n\nNICE-TO-HAVES\n\n - Experience working in early-stage startups and shaping product from 0 to 1.\n\n - Background in healthcare, life sciences, or other regulated industries.\n\n - Familiarity with cloud infrastructure (AWS/GCP), CI/CD pipelines, and monitoring/observability tools.\n\n - Exposure to AI-driven products or agentic systems.\n\n\n\nCompensation Philosophy\n\nCompensation for this position will include a base salary, equity, and a variety of comprehensive benefits. The U.S. base salary range for this role is $160,000 - $270,000. Actual base salaries will be based on candidate-specific factors, including experience, skillset, and location, and local minimum pay requirements as applicable.\n\n \n\nBenefits & Perks\n\nAs part of our total rewards package, we offer attractive benefits and perks to our employees, including:\n\n - Free lunch in the office daily & dinner if you're in the office past 7PM\n\n - Comprehensive health, dental, & vision insurance for you and your family\n\n - Life insurance\n\n - 10 company holidays\n\n - Take what you need PTO \n\n - 4% 401k matching\n\n - $300/month company-sponsored commuter benefits\n\n - State of the art gym in the office\n\n - And more!\n\nPlease note the above benefits & perks are for full-time employees"},{"id":"3fc505f8-b8cf-4cdb-b3b2-6d3a5a7a73fb","title":"Member of Technical Staff, Infrastructure","department":"Engineering","team":"Infrastructure","employmentType":"FullTime","location":"San Francisco","secondaryLocations":[],"publishedAt":"2026-05-21T18:09:58.209+00:00","isListed":true,"isRemote":null,"workplaceType":null,"address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/mandolin/3fc505f8-b8cf-4cdb-b3b2-6d3a5a7a73fb","applyUrl":"https://jobs.ashbyhq.com/mandolin/3fc505f8-b8cf-4cdb-b3b2-6d3a5a7a73fb/application","descriptionHtml":"Nearly every disease will become treatable in our lifetimes. Mandolin is laying the clinical and financial infrastructure to get groundbreaking treatments to patients faster, powered by AI agents.
Mandolin partners closely with the largest healthcare institutions in the US, covering more than $10B drug spend across the country. We're backed by Greylock, SV Angel, Maverick, SignalFire, and the founders of Vercel, Decagon, and Yahoo.
Mandolin’s usage is climbing quickly and we’re preparing for a broad public launch. The platform must deliver enterprise-grade reliability, airtight security, and effortless developer productivity while processing sensitive healthcare data. We’re looking for an Infrastructure Engineer who can build and operate a rock-solid cloud foundation—then codify the best-practice guardrails that every engineer will rely on as we scale.
Own cloud infrastructure end-to-end: Design and operate scalable, highly available environments across development, staging, and production. Establish autoscaling policies, HA networking, cost-efficient resource management, and clear environment parity. We run on GCP today — what matters is how you think about infrastructure, not which cloud you learned on.
Drive GitOps and Kubernetes delivery: Own the GitOps delivery pipeline using ArgoCD and Kubernetes. Manage clusters, ApplicationSets, workload deployments, and promotion workflows across environments. Ensure deployments are reliable, observable, and safely reversible.
Embed security into the SDLC: Centralize secrets management, define zero-trust IAM policies, integrate continuous vulnerability scanning into CI/CD, and own incident-response playbooks. Security is a design input, not an afterthought.
Build first-class observability: Deploy and maintain metrics, tracing, and log pipelines. Define actionable SLOs and alerting so the team knows about problems before customers do.
Improve developer experience: Provide runbooks, local-environment tooling, and clear onboarding patterns that let new engineers ship safely on day one. Reduce toil through automation and golden-path tooling.
Write code that matters: Infrastructure at Mandolin isn't just configuration — you'll write Go to build internal tooling, automate operational workflows, and solve problems that can't be solved with YAML alone.
Collaborate across teams: Review architectural changes for infrastructure and security impact. Partner with backend engineers on scalability initiatives. Document decisions clearly so knowledge doesn't live only in your head.
7+ years building and operating production cloud infrastructure at scale
Deep hands-on experience with Kubernetes — cluster management, workload design, networking, autoscaling, production troubleshooting
GitOps & ArgoCD: Experience with ApplicationSets, sync waves, multi-cluster delivery, promotion workflows
CI/CD experience: GitHub Actions, Cloud Build, or equivalent — pipelines, caching, artifact management, security gates
IAC: Pulumi, Terraform, or equivalent — writing infrastructure as code, not just running it
Secrets Management: centralized stores, ESO or equivalent, automated rotation, zero inline secrets
Security: IAM design, zero-trust principles, vulnerability scanning, dependency management
Experience writing production-quality code in GoLang, functional programming style, not just scripts
Cloud experience: we run on GCP. AWS or Azure experience with strong cloud fundamentals transfers well — you'll need to ramp quickly
Experience with workflow orchestration platforms — Temporal, Argo Workflows, Airflow, or Cadence
Prior work in HIPAA, SOC 2, or similarly regulated environments
Exposure to service mesh, mTLS, or zero-trust networking patterns
Experience building internal developer platforms or golden-path tooling
Background working in healthcare or other data-sensitive industries
Compensation Philosophy
Compensation for this position will include a base salary, equity, and a variety of comprehensive benefits. The U.S. base salary range for this role is $160,000 - $270,000. Actual base salaries will be based on candidate-specific factors, including experience, skillset, and location, and local minimum pay requirements as applicable.
Benefits & Perks
As part of our total rewards package, we offer attractive benefits and perks to our employees, including:
Free lunch in the office daily & dinner if you're in the office past 7PM
Comprehensive health, dental, & vision insurance for you and your family
Life insurance
10 company holidays
Take what you need PTO
4% 401k matching
$300/month company-sponsored commuter benefits
State of the art gym in the office
And more!
Please note the above benefits & perks are for full-time employees
","descriptionPlain":"ABOUT MANDOLIN\n\nNearly every disease will become treatable in our lifetimes. Mandolin is laying the clinical and financial infrastructure to get groundbreaking treatments to patients faster, powered by AI agents.\n\n\n\nMandolin partners closely with the largest healthcare institutions in the US, covering more than $10B drug spend across the country. We're backed by Greylock, SV Angel, Maverick, SignalFire, and the founders of Vercel, Decagon, and Yahoo.\n\n\n\n\nWHY WE NEED YOU\n\nMandolin’s usage is climbing quickly and we’re preparing for a broad public launch. The platform must deliver enterprise-grade reliability, airtight security, and effortless developer productivity while processing sensitive healthcare data. We’re looking for an Infrastructure Engineer who can build and operate a rock-solid cloud foundation—then codify the best-practice guardrails that every engineer will rely on as we scale.\n\n\n\n\nWHAT YOU’LL DO\n\n - Own cloud infrastructure end-to-end: Design and operate scalable, highly available environments across development, staging, and production. Establish autoscaling policies, HA networking, cost-efficient resource management, and clear environment parity. We run on GCP today — what matters is how you think about infrastructure, not which cloud you learned on.\n\n - Drive GitOps and Kubernetes delivery: Own the GitOps delivery pipeline using ArgoCD and Kubernetes. Manage clusters, ApplicationSets, workload deployments, and promotion workflows across environments. Ensure deployments are reliable, observable, and safely reversible.\n\n - Embed security into the SDLC: Centralize secrets management, define zero-trust IAM policies, integrate continuous vulnerability scanning into CI/CD, and own incident-response playbooks. Security is a design input, not an afterthought.\n\n - Build first-class observability: Deploy and maintain metrics, tracing, and log pipelines. Define actionable SLOs and alerting so the team knows about problems before customers do.\n\n - Improve developer experience: Provide runbooks, local-environment tooling, and clear onboarding patterns that let new engineers ship safely on day one. Reduce toil through automation and golden-path tooling.\n\n - Write code that matters: Infrastructure at Mandolin isn't just configuration — you'll write Go to build internal tooling, automate operational workflows, and solve problems that can't be solved with YAML alone.\n\n - Collaborate across teams: Review architectural changes for infrastructure and security impact. Partner with backend engineers on scalability initiatives. Document decisions clearly so knowledge doesn't live only in your head.\n\n\n\n\nMUST-HAVE EXPERIENCE\n\n - 7+ years building and operating production cloud infrastructure at scale\n\n - Deep hands-on experience with Kubernetes — cluster management, workload design, networking, autoscaling, production troubleshooting\n\n - GitOps & ArgoCD: Experience with ApplicationSets, sync waves, multi-cluster delivery, promotion workflows \n\n - CI/CD experience: GitHub Actions, Cloud Build, or equivalent — pipelines, caching, artifact management, security gates\n\n - IAC: Pulumi, Terraform, or equivalent — writing infrastructure as code, not just running it\n\n - Secrets Management: centralized stores, ESO or equivalent, automated rotation, zero inline secrets\n\n - Security: IAM design, zero-trust principles, vulnerability scanning, dependency management\n\n - Experience writing production-quality code in GoLang, functional programming style, not just scripts\n\n - Cloud experience: we run on GCP. AWS or Azure experience with strong cloud fundamentals transfers well — you'll need to ramp quickly\n\n\nNICE-TO-HAVES\n\n - Experience with workflow orchestration platforms — Temporal, Argo Workflows, Airflow, or Cadence\n\n - Prior work in HIPAA, SOC 2, or similarly regulated environments\n\n - Exposure to service mesh, mTLS, or zero-trust networking patterns\n\n - Experience building internal developer platforms or golden-path tooling\n\n - Background working in healthcare or other data-sensitive industries\n\n\n\nCompensation Philosophy\n\nCompensation for this position will include a base salary, equity, and a variety of comprehensive benefits. The U.S. base salary range for this role is $160,000 - $270,000. Actual base salaries will be based on candidate-specific factors, including experience, skillset, and location, and local minimum pay requirements as applicable.\n\n \n\nBenefits & Perks\n\nAs part of our total rewards package, we offer attractive benefits and perks to our employees, including:\n\n - Free lunch in the office daily & dinner if you're in the office past 7PM\n\n - Comprehensive health, dental, & vision insurance for you and your family\n\n - Life insurance\n\n - 10 company holidays\n\n - Take what you need PTO \n\n - 4% 401k matching\n\n - $300/month company-sponsored commuter benefits\n\n - State of the art gym in the office\n\n - And more!\n\nPlease note the above benefits & perks are for full-time employees"}],"apiVersion":"1"}